Home / Vaccinations / Japanese Encephalitis Vaccine
Travel vaccineJapanese encephalitis is a mosquito-borne infection of the brain, and the leading cause of viral encephalitis across Asia. Most infections are silent — but when the brain is affected, the consequences can be devastating. Vaccination is the most effective protection for those travelling to rural Asia.
Japanese encephalitis (JE) is a viral infection of the brain, caused by a flavivirus and spread by the bite of infected Culex mosquitoes. These mosquitoes breed in flooded rice fields, and the virus circulates between water birds and pigs — which is why risk concentrates in rural, agricultural areas.
It is the leading cause of viral encephalitis in Asia and the Western Pacific, and is endemic in around 24 countries. Singapore itself is not a risk area.
There is no specific antiviral treatment. Care is supportive only, which is why prevention matters so much.
We provide IMOJEV, a live, weakened vaccine given as a single dose. Whether it is right for you depends on your health, your age and where you're travelling.
Because this is a live vaccine, it is not suitable for everyone. An inactivated — non-live — Japanese encephalitis vaccine also exists and is available elsewhere in Singapore, but we do not carry it. If it is the safer choice for you, our doctors will say so at your consultation and point you in the right direction.
Risk depends on destination, duration, season and what you'll be doing.
A short stay in a modern city hotel carries little risk. Cycling through rice-farming country in the rainy season is a different matter. Tell us your actual plans, not just the country.
The vaccine is given as an injection. Start early — protection needs time to develop before you fly.
Come and see us 4 to 6 weeks before you fly. If your trip is sooner, come anyway — we can still advise on vaccination and on bite prevention.
The vaccine protects against Japanese encephalitis. It does nothing for dengue, chikungunya or Zika — carried by mosquitoes in the same places.
The Culex mosquitoes that spread JE bite mainly between dusk and dawn, and are most numerous around rice paddies and animal farms. Vaccination reduces your risk of one serious disease. Avoiding bites reduces your risk of several.
If you develop a fever, severe headache, confusion or neck stiffness during or after travel to an affected area, seek medical attention immediately and say where you have been.
Most people tolerate the vaccine well. Reactions are usually mild and short-lived.
Severe allergic reactions are rare. Get medical attention immediately if you develop hives, swelling of the face or throat, difficulty breathing, a fast heartbeat, dizziness or weakness after vaccination.
The Japanese encephalitis vaccine is a travel vaccine and is self-funded — it isn't covered by CHAS, Healthier SG or other national subsidy schemes. It is among the more expensive travel vaccines. Ask us for the price, and about your other travel vaccines at the same time.
One travel consultation covers everything you need before you fly.
Destination, dates, how rural your itinerary is, and where you'll sleep.
We assess your risk and confirm whether the vaccine is suitable for you.
A single injection, given at the clinic.
Documented in your health record for your travel documentation.
Book a travel consultation 4 to 6 weeks before you fly. We'll advise whether the Japanese encephalitis vaccine is warranted, and cover your other travel health needs in one visit.
Book a travel consultationThe requirements and recommendations on this page are drawn from official Singapore government sources:
This page is general information, not medical advice, and requirements can change. Always confirm the current position with the relevant Singapore government agency, or speak to our doctors about your own circumstances.