Home / Vaccinations / Hepatitis A and B Vaccine
Routine & travel vaccineHepatitis A and hepatitis B are viral infections that attack the liver. Both are preventable by vaccination. Our doctors give the hepatitis A vaccine, the hepatitis B vaccine, or the combined hepatitis A and B vaccine (Twinrix) — whichever suits your travel, work or health needs.
Both are viral infections that inflame the liver, and they share many symptoms — but they spread differently and behave very differently.
Hepatitis A (HAV) spreads through food or water contaminated with faeces — including raw or undercooked shellfish from polluted waters. It causes a short-term illness that resolves on its own, and never becomes chronic. Once you recover, you're immune for life.
Hepatitis B (HBV) spreads through blood and body fluids — unprotected sex, shared needles, unsterile tattooing or piercing, and from mother to baby at birth. It can become a lifelong chronic infection that quietly damages the liver, raising the risk of cirrhosis and liver cancer.
Two different viruses, two different vaccines. Here's how they compare.
| Hepatitis A | Hepatitis B | |
|---|---|---|
| How it spreads | Contaminated food and water; raw shellfish; poor hand hygiene. | Blood and body fluids; unprotected sex; shared needles; mother to baby at birth. |
| Becomes chronic? | No — a short-term illness that resolves on its own. | Yes — can become a lifelong infection. |
| Long-term risk | Rarely, acute liver failure. | Cirrhosis, liver failure and liver cancer. |
| Vaccine course | 2 doses, 6–12 months apart. | 3 doses, at 0, 1 and 6 months. |
| Protection | At least 20 years, likely lifelong. | 20–30 years, often lifelong. |
| In Singapore | Mainly recommended for travel and higher-risk groups. | Nationally recommended — given at birth since 1987. |
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Vaccination is recommended based on your age, travel plans, work and health history.
Each vaccine is an injection into the upper arm (or the thigh, for infants). Your doctor will recommend the right course.
Protects against the food- and water-borne hepatitis A virus. Recommended from 12 months of age, and widely advised before travel.
Protects against the blood-borne hepatitis B virus, the one that can turn chronic. Given to newborns in Singapore since 1987, and to unvaccinated adults.
One course, both viruses. Convenient if you need protection against hepatitis A and B — fewer injections and a single schedule.
Already vaccinated, or unsure? A simple blood test can show whether you are already immune to hepatitis B, or whether you are a carrier. Our doctors will advise whether testing is worthwhile before you start a course.
Both vaccines are given as a short series over several months.
Both vaccines are inactivated (non-live) and have a long safety record.
Severe allergic reactions are rare. Get medical attention immediately if you develop swelling of the face, eyes, lips or tongue, difficulty breathing, or a widespread itchy rash after vaccination.
Hepatitis B is nationally recommended, so several schemes help with the cost. Hepatitis A is usually self-funded.
Hepatitis B is given free to newborns under the National Childhood Immunisation Schedule, with subsidies for eligible children.
Nationally recommended vaccinations, including hepatitis B, are fully subsidised for eligible enrollees at their enrolled clinic.
Subsidised hepatitis B vaccination at CHAS GP clinics for eligible cardholders under NAIS.
Can be used towards nationally recommended vaccinations, including the hepatitis B vaccine.
We'll plan your course and remind you when each dose is due.
We check your history, travel plans and whether a blood test would help.
A quick injection into the upper arm, over in seconds.
We schedule your remaining doses and remind you when they're due.
Logged to the National Immunisation Registry and your HealthHub record.
Book your hepatitis A vaccine, hepatitis B vaccine, or the combined hepatitis A and B vaccine at any of our clinics.
Book your hepatitis vaccineThe requirements and recommendations on this page are drawn from official Singapore government sources:
This page is general information, not medical advice, and requirements can change. Always confirm the current position with the relevant Singapore government agency, or speak to our doctors about your own circumstances.