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Routine & travel vaccine

Hepatitis A and B Vaccine in Singapore

Hepatitis A and hepatitis B are viral infections that attack the liver. Both are preventable by vaccination. Our doctors give the hepatitis A vaccine, the hepatitis B vaccine, or the combined hepatitis A and B vaccine (Twinrix) — whichever suits your travel, work or health needs.

A & BLiver protection
TwinrixBoth in one course
20+ yrsLong-lasting protection
AccessibleClinics across Singapore
A vial of hepatitis vaccine with a syringe
The diseases

What are hepatitis A and hepatitis B?

Both are viral infections that inflame the liver, and they share many symptoms — but they spread differently and behave very differently.

Hepatitis A (HAV) spreads through food or water contaminated with faeces — including raw or undercooked shellfish from polluted waters. It causes a short-term illness that resolves on its own, and never becomes chronic. Once you recover, you're immune for life.

Hepatitis B (HBV) spreads through blood and body fluids — unprotected sex, shared needles, unsterile tattooing or piercing, and from mother to baby at birth. It can become a lifelong chronic infection that quietly damages the liver, raising the risk of cirrhosis and liver cancer.

Symptoms of hepatitis

  • Fatigue and loss of appetite
  • Nausea, vomiting and abdominal pain
  • Jaundice — yellowing of the skin and eyes
  • Dark urine and pale stools
  • Fever and joint pain
  • Often no symptoms at all — especially young children, and chronic hepatitis B
Know the difference

Hepatitis A vs hepatitis B

Two different viruses, two different vaccines. Here's how they compare.

 Hepatitis AHepatitis B
How it spreadsContaminated food and water; raw shellfish; poor hand hygiene.Blood and body fluids; unprotected sex; shared needles; mother to baby at birth.
Becomes chronic?No — a short-term illness that resolves on its own.Yes — can become a lifelong infection.
Long-term riskRarely, acute liver failure.Cirrhosis, liver failure and liver cancer.
Vaccine course2 doses, 6–12 months apart.3 doses, at 0, 1 and 6 months.
ProtectionAt least 20 years, likely lifelong.20–30 years, often lifelong.
In SingaporeMainly recommended for travel and higher-risk groups.Nationally recommended — given at birth since 1987.

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Is it for you?

Who should get the hepatitis A and B vaccine?

Vaccination is recommended based on your age, travel plans, work and health history.

  • All infants and children — hepatitis B from birth, hepatitis A from 12 months
  • Adults 18+ never vaccinated against hepatitis B
  • Travellers to regions where hepatitis is common
  • Healthcare, laboratory and sewage workers
  • People with chronic liver disease
  • Household and sexual contacts of someone with hepatitis B
  • People on dialysis, or receiving regular blood products
  • Those with multiple sexual partners, or who inject drugs
The vaccines

Hepatitis A vaccine, hepatitis B vaccine, or both?

Each vaccine is an injection into the upper arm (or the thigh, for infants). Your doctor will recommend the right course.

2doses

Hepatitis A vaccine

e.g. Havrix

Protects against the food- and water-borne hepatitis A virus. Recommended from 12 months of age, and widely advised before travel.

  • First dose, then a booster 6–12 months later
  • Protection at least 20 years, likely lifelong
  • Usually self-funded
3doses

Hepatitis B vaccine

e.g. Engerix-B

Protects against the blood-borne hepatitis B virus, the one that can turn chronic. Given to newborns in Singapore since 1987, and to unvaccinated adults.

  • Doses at 0, 1 and 6 months
  • Protection 20–30 years, often lifelong
  • Nationally recommended — subsidies apply
3doses

Hepatitis A and B vaccine

Twinrix · combined

One course, both viruses. Convenient if you need protection against hepatitis A and B — fewer injections and a single schedule.

  • Three doses over six months
  • Accelerated schedule for urgent travel
  • Covers both A and B

Already vaccinated, or unsure? A simple blood test can show whether you are already immune to hepatitis B, or whether you are a carrier. Our doctors will advise whether testing is worthwhile before you start a course.

Schedule

Hepatitis vaccine doses & schedule

Both vaccines are given as a short series over several months.

Hepatitis A vaccineTwo doses. The second is given about 6 to 12 months after the first. Children can start from 12 months of age.
Hepatitis B vaccine — adultsThree doses: the second one month after the first, the third about six months after the first.
Hepatitis B vaccine — infantsUnder the National Childhood Immunisation Schedule, the first dose is given at birth, with the course completed by about six months of age.
Combined hepatitis A and B (Twinrix)Three doses over six months. An accelerated schedule is available if you're travelling soon.
Safety

Hepatitis vaccine side effects & precautions

Both vaccines are inactivated (non-live) and have a long safety record.

Common & mild

  • Pain, redness or swelling at the injection site
  • Headache, tiredness or mild fever
  • Loss of appetite, nausea or an upset stomach
  • Usually settles within a day or two

Tell your doctor if you

  • Are unwell or have a fever today
  • Reacted badly to a previous hepatitis vaccine or any of its ingredients
  • Are pregnant, planning a pregnancy, or breastfeeding
  • Have a bleeding disorder, or take blood thinners
  • Have a weakened immune system, or take immunosuppressive medicines

Seek help promptly for severe reactions

Severe allergic reactions are rare. Get medical attention immediately if you develop swelling of the face, eyes, lips or tongue, difficulty breathing, or a widespread itchy rash after vaccination.

Cost

Hepatitis A and B vaccine cost & subsidies in Singapore

Hepatitis B is nationally recommended, so several schemes help with the cost. Hepatitis A is usually self-funded.

Children (NCIS)

Hepatitis B is given free to newborns under the National Childhood Immunisation Schedule, with subsidies for eligible children.

Healthier SG

Nationally recommended vaccinations, including hepatitis B, are fully subsidised for eligible enrollees at their enrolled clinic.

CHAS & Pioneer / Merdeka

Subsidised hepatitis B vaccination at CHAS GP clinics for eligible cardholders under NAIS.

MediSave

Can be used towards nationally recommended vaccinations, including the hepatitis B vaccine.

 Ask about hepatitis vaccine pricing
What to expect

Getting your hepatitis vaccination

We'll plan your course and remind you when each dose is due.

1. Quick review

We check your history, travel plans and whether a blood test would help.

2. Your first dose

A quick injection into the upper arm, over in seconds.

3. Complete the course

We schedule your remaining doses and remind you when they're due.

4. Recorded for you

Logged to the National Immunisation Registry and your HealthHub record.

Good to know

Hepatitis A and B vaccine FAQs

Do I need both the hepatitis A and B vaccines?
They protect against two different viruses, so one does not cover the other. If you need protection against both — for travel, work or lifestyle reasons — you can have them separately, or as a combined hepatitis A and B vaccine (Twinrix) in a single course.
What is the combined hepatitis A and B vaccine?
Twinrix is a combined vaccine that protects against both hepatitis A and hepatitis B in one course, usually three doses over six months. It means fewer injections and one schedule to remember. An accelerated schedule is available if you're travelling soon.
How many doses of the hepatitis B vaccine do I need?
Adults who have not been vaccinated typically need three doses of the hepatitis B vaccine — the second a month after the first, and the third about six months after the first. Infants receive their first dose at birth under the childhood schedule.
How many doses of the hepatitis A vaccine do I need?
Two doses. The second is given about 6 to 12 months after the first, which completes the course and gives long-lasting protection.
How long does the hepatitis A and B vaccine last?
Protection is long-lasting. The hepatitis A vaccine generally protects for at least 20 years and possibly for life. The hepatitis B vaccine typically protects for 20 to 30 years, with many people protected for life. Booster doses are rarely needed after a completed course.
Is the hepatitis B vaccine free or subsidised in Singapore?
Hepatitis B vaccination is nationally recommended. It is given free to newborns under the National Childhood Immunisation Schedule, and subsidies apply for eligible children and adults at CHAS GP clinics, for Pioneer and Merdeka Generation cardholders, and for Healthier SG enrollees. Most adults will pay something, so contact us to check what you qualify for.
Can I use MediSave for the hepatitis B vaccine?
Yes. MediSave can be used for nationally recommended vaccinations under the National Adult Immunisation Schedule (NAIS), which includes the hepatitis B vaccine, for eligible Singapore Citizens and Permanent Residents.
Is the hepatitis A vaccine subsidised?
The hepatitis A vaccine is generally recommended for travel and for higher-risk groups rather than the whole population, so it is usually self-funded. Our team will confirm the cost when you book.
Do I need a blood test before the hepatitis B vaccine?
Sometimes. A blood test can show whether you are already immune, or whether you are a hepatitis B carrier — useful if you were vaccinated long ago, or if there is hepatitis B in your family. Our doctors will advise whether testing makes sense for you.
Can I still get hepatitis B after being vaccinated?
It's uncommon. Over 90% of adults under 40 develop protective antibodies after the full course, though this falls to around 75% by age 60. Infection is more likely if the course was never completed or the immune response was poor — a blood test can confirm your protection.
Which is more important, the hepatitis A or hepatitis B vaccine?
Both matter, but hepatitis B carries the greater long-term risk because it can become a chronic infection leading to cirrhosis and liver cancer. Hepatitis A is unpleasant but usually resolves on its own and never becomes chronic.
Is the hepatitis vaccine safe in pregnancy?
Hepatitis A and B vaccines are inactivated (non-live) vaccines. Hepatitis B vaccination is recommended in pregnancy when a woman is at risk of infection. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding, so the right decision can be made for you.
What are the side effects of the hepatitis A and B vaccine?
Most people have only mild effects: soreness, redness or swelling at the injection site, and sometimes headache, tiredness, mild fever, loss of appetite or nausea. These usually settle within a day or two. Severe allergic reactions are rare.
Do I need the hepatitis vaccine for travel?
Hepatitis A is commonly recommended for travel to many parts of Asia, Africa and South America, where it spreads through contaminated food and water. Hepatitis B is advised for longer stays, medical work, or activities with a risk of blood exposure. We'll advise based on your trip.
Where is my vaccination recorded?
Your hepatitis vaccinations are recorded in the National Immunisation Registry and appear in your HealthHub record, so your immunisation history is always available to you and your doctors.
Related

Other vaccines you may need

Protect your liver for the long run

Book your hepatitis A vaccine, hepatitis B vaccine, or the combined hepatitis A and B vaccine at any of our clinics.

Book your hepatitis vaccine

Sources

The requirements and recommendations on this page are drawn from official Singapore government sources:

This page is general information, not medical advice, and requirements can change. Always confirm the current position with the relevant Singapore government agency, or speak to our doctors about your own circumstances.