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Preconception & fertility

twoplus Fertility Supplements in Singapore

Trying for a baby is rarely as simple as anyone expects. twoplus Fertility Complete gives your body the nutritional groundwork for conception — and at Bethesda Medical it comes with something a supplement on its own cannot offer: a doctor who checks what else might be in the way.

90 daysAn egg takes that to mature
Both partnersFertility is a team effort
Doctor-ledAssessment, not just a product
Made in SGThird-party lab tested
A doctor discussing preconception and fertility plans with a patient
The window

Why the 90 days before conception matter

An egg does not appear on the day you ovulate. It has been developing for roughly 90 days beforehand. Sperm take around two and a half months to form. What both partners eat, take and absorb today is acting on eggs and sperm that will not be in play until months from now.

That is the argument for starting early, and it is why fertility supplements ask for a minimum of three months. A few weeks is not a fair trial — it is testing the wrong batch.

It is also why a standard prenatal is not quite the same thing. Prenatals are designed for a pregnancy already underway. Preconception formulas are aimed at the months before.

Why three months?

  • An egg matures over about 90 days before ovulation
  • Sperm production takes roughly 2.5 months from start to finish
  • Nutrient levels in the body shift over weeks, not days
  • Three months is the shortest sensible trial — for both partners
  • Starting sooner costs nothing but time you were spending anyway
The supplements

twoplus Fertility Complete, for her and for him

twoplus Fertility is a Singapore company founded by Benjamin Tee after his own five-year experience of infertility. Fertility Complete comes as two separate formulas, because what supports egg development is not what supports sperm.

Fertility Complete for Her

An all-in-one preconception formula of 12 nutrients, taken as three capsules daily with food.

  • Myo-inositol and D-chiro-inositol in a 40:1 ratio — studied in relation to hormone balance and regular ovulation
  • CoQ10 — an antioxidant studied in relation to egg quality
  • Folic acid as methylfolate — the one ingredient with firmly established evidence, for reducing neural tube defects
  • Vitamin D, B12, iodine and selenium — nutrients many women are low in before conception
  • Iron, zinc, magnesium and vitamin A — see the safety note below on vitamin A

Fertility Complete for Him

An all-in-one formula of 8 nutrients, also three capsules daily with food.

  • Myo-inositol — studied in relation to sperm movement
  • CoQ10, vitamin C, vitamin E, lycopene and selenium — antioxidants, aimed at oxidative stress on sperm
  • Zinc — involved in sperm production; levels are often lower in subfertile men
  • Folic acid — involved in healthy sperm development
  • Aimed at sperm count, motility and morphology — the three things a semen analysis measures

Both formulas use plant-based capsules, so they suit vegetarians and vegans, and twoplus states they are free from milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy, with no added artificial colours, preservatives, flavours or sweeteners. They are made in Singapore, and every batch is tested by an independent third-party laboratory for microbes and heavy metals.

Straight answer

What a supplement can do — and what it cannot

We would rather you heard this from us now than worked it out three months from now.

What it can do

  • Close nutritional gaps, and gaps are common — a large study around conception found most women low in at least one of folate, vitamin B12 or vitamin D
  • Provide folic acid, which has firmly established evidence for reducing neural tube defects
  • Support egg and sperm development through the months when they are actually forming
  • Give both partners something practical to do together, which matters more than it sounds

What it cannot do

  • Open blocked fallopian tubes, or treat endometriosis, fibroids or adhesions
  • Reverse low ovarian reserve, or change your age
  • Correct a significant sperm problem, or a hormonal condition that needs treatment
  • Guarantee a pregnancy — nothing can, and anything claiming otherwise deserves scepticism
  • Replace an assessment — three months on a supplement is three months not spent finding out
Before you start

Why start with a consultation, not a supplement

Fertility supplements do not need a prescription, so it is perfectly possible to start one on your own. Here is what that route cannot do for you.

Starting on your own

  • You are treating nutrition — without knowing whether nutrition is what is standing in the way
  • Nothing has been measured. Thyroid function, blood sugar, rubella immunity and sperm quality all affect conception and none of them can be felt
  • Nobody has checked it against what you already take — doubling up on iron, iodine or vitamin A has real upper limits
  • It is a one-person decision, when roughly half of the picture belongs to the other partner
  • Three months pass. If nothing changes, you are three months further on with the same unanswered question

Starting after a review

  • The treatable things get found first — an underactive thyroid, undiagnosed diabetes, an overdue cervical screening, a medicine unsafe in pregnancy
  • You know whether the supplement is suitable for you, and whether anything you take already covers it
  • Both partners can be assessed in the same visit
  • You get a timeline, and a clear point at which we refer you on rather than carry on waiting
  • The supplement becomes one part of a plan rather than the whole of it

This is not an argument against supplements — we provide them here. It is an argument against waiting. The threshold for investigating difficulty conceiving is twelve months of trying, or six if the female partner is 35 or older, and a course taken quietly at home is one of the commonest reasons people arrive past it.

Our part

How to improve your chances of conceiving

Our family physicians look at the whole picture, not just the supplement. Several of our doctors hold a particular interest in women’s health, and preconception care is part of routine family medicine for us.

A preconception consultation is short and practical. We look for the things that quietly reduce the odds and are straightforward to put right — an underactive thyroid, undiagnosed diabetes, high blood pressure, an overdue cervical screening, no rubella immunity, a medicine that is not safe in pregnancy.

We will also talk plainly about the things that make the biggest difference and cost nothing: cycle timing, smoking, alcohol and weight. Weight affects ovulation and sperm quality in both directions, and it is one of the few fertility factors genuinely within reach.

And if the picture suggests something a family doctor should not manage alone, we will say so and refer you on. Knowing when to stop trying at home is part of the job.

  • A preconception review for one or both partners
  • Blood tests where indicated — thyroid, blood sugar, rubella immunity, blood count
  • Cervical screening brought up to date, and contraception stopped safely
  • Medicines reviewed for safety in pregnancy, including anything over the counter
  • Chronic conditions optimised before you conceive, rather than after
  • Referral to a fertility specialist when that is the right next step
Before you start

Who should check with a doctor first

  • You are already pregnant — stop the female formula at a positive test and switch to a prenatal
  • You are breastfeeding — twoplus states the female formula is not suitable
  • You take warfarin or another blood thinner, or have surgery planned
  • You take thyroid medicine — iron, iodine and calcium all affect absorption
  • You are already on a prenatal or a prescribed nutrient — compare, do not stack
  • You have an existing medical condition, or are under a fertility specialist

Vitamin A, and why doubling up matters

Fertility Complete for Her contains vitamin A, which is appropriate before conception but not something to continue once you are pregnant — twoplus itself advises stopping at a positive test. The same caution applies to taking two supplements at once: iron, iodine and vitamin A all have upper limits, and two products that each contain a sensible amount can together add up to too much. Bring everything you take to your consultation, including anything bought off the shelf.

Timing

When to see a doctor about difficulty conceiving

There is a point at which trying for longer stops being the answer, and it arrives sooner than most couples assume.

After 12 months of tryingRegular unprotected intercourse for a year without conception, if the female partner is under 35.
After 6 months, if you are 35 or olderEgg numbers and quality decline with age, so the case for looking sooner is stronger.
Straight away, in some situationsIrregular or absent periods, known PCOS or endometriosis, previous pelvic surgery, more than one miscarriage, or previous chemotherapy, radiotherapy or testicular problems in the male partner.

Coming in earlier is never wasted. Even when everything turns out normal, knowing that is worth something — and if it is not, you have found out months sooner.

How it works

Getting started with us

1. Book a consultation

Come as a couple if you can — fertility is rarely one person’s question.

2. Preconception review

History, examination where needed, and any tests that make sense for you.

3. A plan, and the supplement if it fits

We advise on Fertility Complete for her, for him, or both — and on anything else that would help.

4. Review, and refer if needed

We follow up, and refer you to a fertility specialist if that becomes the right step.

Cost

twoplus Fertility supplement cost in Singapore

Health supplements are self-funded and are not claimable under CHAS, Healthier SG or MediSave. We dispense Fertility Complete at the clinic as part of a plan, once a doctor has confirmed it is appropriate for you. Ask us about the cost and the consultation fee together when you book — and bear in mind that a supplement is usually the smaller part of what makes a difference.

FAQ

twoplus Fertility — frequently asked questions

How can I increase my chances of getting pregnant?
Several things genuinely move the odds, and most cost nothing. Time intercourse to the fertile window — the five days before ovulation and the day itself — rather than to a single "best day". Take folic acid, which has firmly established evidence. Stop smoking, and keep alcohol low, for both partners. Get to a healthy weight, since weight affects ovulation and sperm quality in both directions. And have any undiagnosed condition found and treated — an underactive thyroid, diabetes or high blood pressure can quietly reduce your chances, and all are straightforward to put right. A preconception supplement supports the nutritional side of that picture; it is one part of the plan, not the whole of it.
What is twoplus Fertility Complete?
It is a pair of preconception supplements, one formulated for women and one for men, made in Singapore by twoplus Fertility. Every batch is tested by an independent third-party laboratory for microbes and heavy metals. We provide it at our clinics as part of a preconception plan, once a doctor has reviewed whether it suits you.
What is in the twoplus Fertility Complete supplements?
Fertility Complete for Her contains 12 nutrients, including myo-inositol and D-chiro-inositol in a 40:1 ratio, CoQ10, folic acid, vitamin D, vitamin B12, iron, zinc, iodine, selenium, magnesium and vitamin A. Fertility Complete for Him contains 8 nutrients, including myo-inositol, CoQ10, zinc, selenium, folic acid, vitamin C, vitamin E and lycopene. Both are taken as three capsules daily, with or after food.
Do I need to see a doctor, or can I start a fertility supplement on my own?
Fertility supplements are not prescription medicines, so nobody can stop you starting one. The question is whether it is the best use of the next three months. A supplement addresses nutrition; it cannot tell you whether your cycles are ovulatory, whether your thyroid is underactive, whether there is a sperm problem, or whether something structural is in the way. Those need testing, and testing is quick. Our doctors would far rather see you at the start than after a year of trying, and if a supplement is right for you we will provide it here as part of the plan.
How long do I need to take a fertility supplement before it makes a difference?
At least three months, and that is a biological answer rather than a marketing one. An egg takes roughly 90 days to mature before it is released, and sperm take around two and a half months to develop. What you take today is acting on eggs and sperm that will not be in play until months from now, which is why a few weeks is not a fair trial.
Do fertility supplements guarantee I will get pregnant?
No, and you should be wary of anything that suggests otherwise. A supplement closes nutritional gaps and supports the conditions for conception. It cannot open blocked fallopian tubes, treat endometriosis or fibroids, reverse low ovarian reserve, or correct a significant sperm problem. If something structural or hormonal is preventing conception, a supplement will not change it.
Should I see a doctor before starting a fertility supplement?
We would encourage it. A short consultation tells you whether anything else needs attention first — thyroid function, blood sugar, blood pressure, cervical screening, rubella immunity — and whether anything you already take interacts. It also means you are not spending three months on a supplement when the real issue is something a test would have found in a week.
When should we see a doctor about difficulty conceiving?
After 12 months of regular unprotected intercourse without conception, or after 6 months if the female partner is 35 or older. Come sooner if periods are irregular or absent, if there is known PCOS, endometriosis or previous pelvic surgery, if there has been more than one miscarriage, or if either partner has had chemotherapy, radiotherapy or testicular problems.
Can I take the supplement while trying, and during the two-week wait?
Yes. twoplus states that Fertility Complete for Her can be continued through the two-week wait. Stop it once a pregnancy test is positive and switch to a prenatal supplement — the formula contains vitamin A, which is not appropriate to continue into pregnancy. Speak to us about that changeover.
Is it safe while breastfeeding?
No. twoplus states that Fertility Complete for Her is not suitable for breastfeeding mothers. If you are breastfeeding and hoping to conceive again, speak to a doctor about what is appropriate for you instead.
Can I take it with my other medicines?
Check with a doctor first. twoplus specifically flags warfarin and planned surgery. Beyond that, iron, iodine and calcium affect the absorption of thyroid medicine, and taking two products that both contain the same nutrient can push you above safe limits. Bring everything you take to your consultation, including anything bought over the counter.
Can it replace the supplement my doctor already prescribed?
Not without asking. If you are already on a prenatal or a prescribed nutrient, compare the two rather than adding one to the other — doubling up on iron, iodine or vitamin A is a real risk. Our doctors can look at both and tell you which to keep.
Is a fertility supplement suitable if I am having IVF or IUI?
Often yes, but your fertility specialist should have the final say, because IVF protocols include their own medicines. twoplus suggests starting once your cycle is scheduled. If you are under a specialist, tell them exactly what you are taking.
Are the supplements suitable for vegetarians or people with allergies?
The capsules are plant-based, so they suit vegetarians and vegans, and twoplus states the formula is free from milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soy. There are no added artificial colours, preservatives, flavours or sweeteners.
Is this covered by CHAS or Healthier SG?
No. Health supplements are self-funded and are not claimable under CHAS, Healthier SG or MediSave. A consultation with our doctors may be claimable in the usual way — ask us when you book.